The XBridge Premier Protein BEH C4 300 Å columns are tested with the MassPREP Protein Mix Standard QC and optimized for protein separation based on size, hydrophobicity and isoelectric point. Compared to conventional C18 phases, the C4 ligand is less retentive and minimizes protein carryover, increases protein recovery and improves peak capacity.

This column is part of the MaxPeak Premier Class of columns, which provides the chromatographic performance expected from our particle technologies while improving reproducibility, peak shape and recovery for metal-sensitive analytes.

This version of Waters' XBridge Premier Protein BEH C4 column has an inner diameter of 4.6 mm, a length of 50 mm and a particle size of 2.5 µm.

XBridge Premier columns prevent unwanted analyte-surface interactions with powerful MaxPeak HPS technology. It is designed to improve recovery, sensitivity and reproducibility by minimizing analyte-surface interactions that can lead to sample loss.

The XBridge Premier columns are an evolution of Waters XBridge XP (eXtended Performance) columns and XBridge HPLC columns, combining the industry-leading column stability of ethylene-bridged hybrid particles (BEH) with MaxPeak High Performance Surfaces (HPS) technology.