Puromycin Aminonucleoside 1g

Puromycin Aminonucleoside is the aminonucleoside portion of Puromycin.  It is a Puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring.  The compound is used in animal models of nephrosis and can induce apoptosis.  It has antineoplastic properties.  Puromycin was isolated from Streptomyces alboniger in the 1950s. Puromycin is routinely used in cell culture as a selective agent in transfection and transformation protocols to select for cells that have been transformed with the pac gene and express puromycin-N-acetyl-transferase.  Puromycin Aminonucleoside is soluble in water.

We also offer:

• Puromycin (P097)
• Puromycin Dihydrochloride (P001)
• Puromycin DiHCl Solution (10 mg/ml in 20 mM HEPES)(P025-P026)

CAS Number: 58-60-6

Molecular Formula: C12H18N6O3

Molecular Weight: 294.31 g/mol

Mechanism of Action: Puromycin Aminonucleoside interferes with protein synthesis, terminating the ribosomal chain.

Storage Conditions: 2-8 °C

Tariff Code: 2941.90.1010